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Title: Additive manufacturing of PLA-based scaffolds intended for bone regeneration and strategies to improve their biological properties
Authors: Donate González, Ricardo 
Monzón Verona, Mario Domingo 
Alemán Domínguez, María Elena 
UNESCO Clasification: 3314 Tecnología médica
331212 Ensayo de materiales
331401 Órganos artificiales
Keywords: Bone Tissue Engineering
Composite Materials
Polylactic Acid
Issue Date: 2020
Journal: E-Polymers 
Abstract: Polylactic acid (PLA) is one of the most commonly used materials in the biomedical sector because of its processability, mechanical properties and biocompatibility. Among the different techniques that are feasible to process this biomaterial, additive manufacturing (AM) has gained attention recently, as it provides the possibility of tuning the design of the structures. This flexibility in the design stage allows the customization of the parts in order to optimize their use in the tissue engineering field. In the recent years, the application of PLA for the manufacture of bone scaffolds has been especially relevant, since numerous studies have proven the potential of this biomaterial for bone regeneration. This review contains a description of the specific requirements in the regeneration of bone and how the state of the art have tried to address them with different strategies to develop PLA-based scaffolds by AM techniques and with improved biofunctionality.
ISSN: 1618-7229
DOI: 10.1515/epoly-2020-0046
Source: E-Polymers[EISSN 1618-7229],v. 20 (1), p. 571-599, (Enero 2020)
Appears in Collections:Reseña
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