Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/75451
Título: Randomized study comparing everolimus- and sirolimus-eluting stents in patients with bifurcation lesions treated by provisional side-branch stenting
Autores/as: Pan, Manuel
Medina, Alfonso
Suarez de Lezo, Jose
Romero, Miguel
Segura, Jose
Martin, Pedro 
Suarez de Lezo, Javier
Hernández Ortega, Enrique 
Mazuelos, Francisco
Ojeda, Soledad
Clasificación UNESCO: 320501 Cardiología
Palabras clave: Coronary Bifurcations
Metaanalysis
Strategy
Cypher
Trial, et al.
Fecha de publicación: 2012
Publicación seriada: Catheterization and Cardiovascular Interventions 
Resumen: Objectives To compare the efficacy of sirolimus- and everolimus-eluting stents in patients with bifurcation lesions treated with provisional side-branch stenting. Background The efficacy of everolimus-eluting stents in bifurcation lesions has been poorly tested. Methods Patients with all types of Medina bifurcation lesions were randomly assigned to treatment with either a sirolimus- (n = 145) or everolimus-eluting stent (n = 148). We included patients with main vessel diameter over 2.5 mm and side branches over 2.25 mm. Patients with diffuse side-branch stenosis were excluded. Results There were no significant differences between patients from the sirolimus and everolimus groups in terms of age, risk factors, clinical status, location of the bifurcation lesions or angiographic variables. Immediate results and in-hospital outcome were also similar in both groups of patients. In-hospital death occurred in two patients, one from each group. Target lesion revascularization was required in nine patients: four patients (2.7%) from the sirolimus group and five patients (3.4%) from the everolimus group. Late cardiac mortality occurred in two patients from the sirolimus group and in one patient from the everolimus group. Major cardiac event rates at 1 year were similar in both groups: nine patients (6.2%) in the sirolimus group and nine patients (6.1%) from the everolimus group (p: ns). Conclusions In patients with bifurcation lesions, no significant differences in clinical outcome at 1-year follow-up were observed between sirolimus- and everolimus-eluting stent groups.
URI: http://hdl.handle.net/10553/75451
ISSN: 1522-1946
DOI: 10.1002/ccd.24281
Fuente: Catheterization And Cardiovascular Interventions [ISSN 1522-1946], v. 80 (7), p. 1165-1170, (Diciembre 2012)
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