Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/70320
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dc.contributor.authorMartínez-González, Miguel A.en_US
dc.contributor.authorFernandez-Lazaro, Cesar I.en_US
dc.contributor.authorToledo, Estefaníaen_US
dc.contributor.authorDíaz-López, Andrésen_US
dc.contributor.authorCorella, Doloresen_US
dc.contributor.authorGoday, Alberten_US
dc.contributor.authorRomaguera, Doraen_US
dc.contributor.authorVioque, Jesúsen_US
dc.contributor.authorAlonso-Gómez, Ángel M.en_US
dc.contributor.authorWärnberg, Juliaen_US
dc.contributor.authorMartínez, J. Alfredoen_US
dc.contributor.authorSerra-Majem, Luísen_US
dc.contributor.authorEstruch, Ramonen_US
dc.contributor.authorTinahones, Francisco J.en_US
dc.contributor.authorLapetra, Joséen_US
dc.contributor.authorPintó, Xavieren_US
dc.contributor.authorTur, Josep A.en_US
dc.contributor.authorLópez-Miranda, Joséen_US
dc.contributor.authorCano-Ibáñez, Naomien_US
dc.contributor.authorDelgado-Rodríguez, Miguelen_US
dc.contributor.authorMatía-Martín, Pilaren_US
dc.contributor.authorDaimiel, Lidiaen_US
dc.contributor.authorSánchez, Vicente Martínen_US
dc.contributor.authorVidal, Josepen_US
dc.contributor.authorVázquez, Clotildeen_US
dc.contributor.authorRos, Emilioen_US
dc.contributor.authorBuil-Cosiales, Pilaren_US
dc.contributor.authorPortoles, Olgaen_US
dc.contributor.authorSoria-Florido, Maríaen_US
dc.contributor.authorKonieczna, Jadwigaen_US
dc.contributor.authorNavarrete-Muñoz, Eva M.en_US
dc.contributor.authorTojal-Sierra, Lucasen_US
dc.contributor.authorFernández-García, José C.en_US
dc.contributor.authorAbete, Itziaren_US
dc.contributor.authorHenríquez-Sánchez, Patriciaen_US
dc.contributor.authorMuñoz-Garach, Aracelien_US
dc.contributor.authorSantos-Lozano, José M.en_US
dc.contributor.authorCorbella, Emilien_US
dc.contributor.authorBibiloni, Maria Del Maren_US
dc.contributor.authorBecerra-Tomás, Nereaen_US
dc.contributor.authorBarragán, Rocíoen_US
dc.contributor.authorCastañer, Olgaen_US
dc.contributor.authorFiol, Miquelen_US
dc.contributor.authorGarcía de la Hera, Manolien_US
dc.contributor.authorBelló-Mora, María C.en_US
dc.contributor.authorGea, Alfredoen_US
dc.contributor.authorBabio, Nancyen_US
dc.contributor.authorFitó, Montseen_US
dc.contributor.authorRuiz-Canela, Miguelen_US
dc.contributor.authorZazpe, Itziaren_US
dc.contributor.authorSalas-Salvadó, Jordien_US
dc.date.accessioned2020-02-16T07:28:51Z-
dc.date.available2020-02-16T07:28:51Z-
dc.date.issued2020en_US
dc.identifier.issn0002-9165en_US
dc.identifier.otherScopus-
dc.identifier.urihttp://hdl.handle.net/10553/70320-
dc.description.abstractBACKGROUND: Overall quality of dietary carbohydrate intake rather than total carbohydrate intake may determine the risk of cardiovascular disease (CVD). OBJECTIVE: We examined 6- and 12-mo changes in carbohydrate quality index (CQI) and concurrent changes in several CVD risk factors in a multicenter, randomized, primary-prevention trial (PREDIMED-Plus) based on an intensive weight-loss lifestyle intervention program. METHODS: Prospective analysis of 5373 overweight/obese Spanish adults (aged 55-75 y) with metabolic syndrome (MetS). Dietary intake information obtained from a validated 143-item semiquantitative food-frequency questionnaire was used to calculate 6- and 12-mo changes in CQI (categorized in quintiles), based on 4 criteria (total dietary fiber intake, glycemic index, whole grain/total grain ratio, and solid carbohydrate/total carbohydrate ratio). The outcomes were changes in intermediate markers of CVD. RESULTS: During the 12-mo follow-up, the majority of participants improved their CQI by increasing their consumption of fruits, vegetables, legumes, fish, and nuts and decreasing their consumption of refined cereals, added sugars, and sugar-sweetened beverages. After 6 mo, body weight, waist circumference (WC), systolic and diastolic blood pressure (BP), fasting blood glucose, glycated hemoglobin (HbA1c), triglyceride levels, triglycerides and glucose (TyG) index, and TyG-WC decreased across successive quintiles of improvement in the CQI. After 12 mo, improvements were additionally observed for HDL cholesterol and for the ratio of total to HDL cholesterol. Favorable improvements (expressed in common units of SD and 95% CI) for quintile 5 compared with quintile 1 of CQI change were observed for most risk factors, including TyG-WC (SD -0.20; 95% CI -0.26, -0.15), HbA1c (SD -0.16; 95% CI -0.23, -0.10), weight (SD -0.12; 95% CI -0.14, -0.09), systolic BP (SD -0.11; 95% CI -0.19, -0.02) and diastolic BP (SD -0.11; 95% CI -0.19, -0.04). CONCLUSIONS: Improvements in CQI were strongly associated with concurrent favorable CVD risk factor changes maintained over time in overweight/obese adults with MetS. This trial was registered as ISRCTN 89898870.en_US
dc.languageengen_US
dc.relation.ispartofThe American journal of clinical nutritionen_US
dc.sourceThe American journal of clinical nutrition [0002-9165], v. 111 (2), p. 291-306en_US
dc.subject320501 Cardiologíaen_US
dc.subject3206 Ciencias de la nutriciónen_US
dc.subject.otherCarbohydrateen_US
dc.subject.otherCarbohydrate Quality Indexen_US
dc.subject.otherCardiovascular Diseaseen_US
dc.subject.otherFiberen_US
dc.subject.otherGlycemic Indexen_US
dc.subject.otherObesityen_US
dc.subject.otherPredimed-Plusen_US
dc.subject.otherRandomized Controlled Trialsen_US
dc.titleCarbohydrate quality changes and concurrent changes in cardiovascular risk factors: a longitudinal analysis in the PREDIMED-Plus randomized trialen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1093/ajcn/nqz298
dc.identifier.scopus85079017957-
dc.identifier.isi000518429700012
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dc.description.lastpage306-
dc.identifier.issue2-
dc.description.firstpage291-
dc.relation.volume111-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
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dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Martinez-Gonzalez, MA
dc.contributor.wosstandardWOS:Fernandez-Lazaro, CI
dc.contributor.wosstandardWOS:Toledo, E
dc.contributor.wosstandardWOS:Diaz-Lopez, A
dc.contributor.wosstandardWOS:Corella, D
dc.contributor.wosstandardWOS:Goday, A
dc.contributor.wosstandardWOS:Romaguera, D
dc.contributor.wosstandardWOS:Vioque, J
dc.contributor.wosstandardWOS:Alonso-Gomez, AM
dc.contributor.wosstandardWOS:Warnberg, J
dc.contributor.wosstandardWOS:Martinez, JA
dc.contributor.wosstandardWOS:Serra-Majem, L
dc.contributor.wosstandardWOS:Estruch, R
dc.contributor.wosstandardWOS:Tinahones, FJ
dc.contributor.wosstandardWOS:Lapetra, J
dc.contributor.wosstandardWOS:Pinto, X
dc.contributor.wosstandardWOS:Tur, JA
dc.contributor.wosstandardWOS:Lopez-Miranda, J
dc.contributor.wosstandardWOS:Cano-Ibanez, N
dc.contributor.wosstandardWOS:Delgado-Rodriguez, M
dc.contributor.wosstandardWOS:Matia-Martin, P
dc.contributor.wosstandardWOS:Daimiel, L
dc.contributor.wosstandardWOS:Sanchez, VM
dc.contributor.wosstandardWOS:Vidal, J
dc.contributor.wosstandardWOS:Vazquez, C
dc.contributor.wosstandardWOS:Ros, E
dc.contributor.wosstandardWOS:Buil-Cosiales, P
dc.contributor.wosstandardWOS:Portoles, O
dc.contributor.wosstandardWOS:Soria-Florido, M
dc.contributor.wosstandardWOS:Konieczna, J
dc.contributor.wosstandardWOS:Navarrete-Munoz, EM
dc.contributor.wosstandardWOS:Tojal-Sierra, L
dc.contributor.wosstandardWOS:Fernandez-Garcia, JC
dc.contributor.wosstandardWOS:Abete, I
dc.contributor.wosstandardWOS:Henriquez-Sanchez, P
dc.contributor.wosstandardWOS:Munoz-Garach, A
dc.contributor.wosstandardWOS:Santos-Lozano, JM
dc.contributor.wosstandardWOS:Corbella, E
dc.contributor.wosstandardWOS:Bibiloni, MD
dc.contributor.wosstandardWOS:Becerra-Tomas, N
dc.contributor.wosstandardWOS:Barragan, R
dc.contributor.wosstandardWOS:Castaner, O
dc.contributor.wosstandardWOS:Fiol, M
dc.contributor.wosstandardWOS:de la Hera, MG
dc.contributor.wosstandardWOS:Bello-Mora, MC
dc.contributor.wosstandardWOS:Gea, A
dc.contributor.wosstandardWOS:Babio, N
dc.contributor.wosstandardWOS:Fito, M
dc.contributor.wosstandardWOS:Ruiz-Canela, M
dc.contributor.wosstandardWOS:Zazpe, I
dc.contributor.wosstandardWOS:Salas-Salvado, J
dc.date.coverdateFebrero 2020
dc.identifier.ulpgces
dc.description.sjr2,704
dc.description.jcr6,766
dc.description.sjrqQ1
dc.description.jcrqQ1
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptNutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Clínicas-
crisitem.author.deptNutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Clínicas-
crisitem.author.orcid0000-0002-9658-9061-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameSerra Majem, Luis-
crisitem.author.fullNameHenríquez Sánchez, Patricia-
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