Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/70181
Título: Pre- and post-surgical evaluation of plasma lactate concentration in 45 dogs with gastric dilatation-volvulus: A preliminary study
Autores/as: Grassato, Lisa
Spinella, Giuseppe
Musella, Vincenzo
Giunti, Massimo
Vilar Guereño, José Manuel 
Valentini, Simona
Clasificación UNESCO: 310907 Patología
Palabras clave: Abdominal Surgery
Dog
Emergency Medicine
Gastric Dilatation-Volvulus
Gastric Necrosis, et al.
Fecha de publicación: 2020
Publicación seriada: Heliyon 
Resumen: This preliminary study was designed to contribute to the evaluation of reliability of plasma lactate concentration (PLC) and its clearance as predictive and prognostic factors of gastric necrosis and clinical outcome of dogs affected by gastric dilatation-volvulus (GDV). Main aims of the study were: 1) to evaluate the prognostic reliability of PLC at presentation (T0) in dogs with GDV, 2) to compare the obtained data and considerations with the veterinary literature, and 3) to introduce the possible validity of PLC values at 24 (T24) and 48 (T48) hours after surgery as a predictive factor. Dogs with GDV were retrospectively evaluated. PLC at T0, T24 and T48 were recorded and correlated to the presence or absence of macroscopic necrosis of the stomach and to outcome. Forty-five dogs met the inclusion criteria. Significant differences were not detected in the mean values between the initial PLC in dogs with and without necrosis of the gastric wall, as well as between surviving and non-surviving dogs; these values were not associated with higher risk of gastric necrosis or death. At T24 and T48 no significant differences were recorded between necrosis and non-necrosis, and surviving and non-surviving categories. A median plasma lactate concentration clearance from arrival to T24 ≥ 50% was identified in both groups (with and without necrosis), and this parameter failed in identifying dogs that survived to discharge. In conclusion, the results presented here failed to detect PLC at T0 and its clearance at T24 as prognostic factors in this population of dogs with GDV.
URI: http://hdl.handle.net/10553/70181
ISSN: 2405-8440
DOI: 10.1016/j.heliyon.2020.e03307
Fuente: Heliyon [ISSN 2405-8440], v. 6 (1)
Colección:Artículos
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