Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/69768
Título: Monitoring Progress of Parkinson's Disease Based on Changes in Phonation: A Pilot Study
Autores/as: Galaz, Zoltan
Mekyska, Jiri
Kiska, Tomas
Zvoncak, Vojtech
Mucha, Jan
Harar, Pavol
Smekal, Zdenek
Eliasova, Ilona
Mrackova, Martina
Kostalova, Milena
Rektorova, Irena
Faundez-Zanuy, Marcos
Alonso-Hernandez, Jesus B. 
Gomez-Vilda, Pedro
Clasificación UNESCO: 32 Ciencias médicas
Palabras clave: Acoustic Analysis
Follow-Up Study
Hypokinetic Dysarthria
Parkinson'S Disease
Phonation
Fecha de publicación: 2018
Publicación seriada: 2018 41St International Conference On Telecommunications And Signal Processing, Tsp 2018
Conferencia: 41st International Conference on Telecommunications and Signal Processing, TSP 2018 
Resumen: Hypokinetic dysarthria (HD) is a frequent symptom of idiopathic Parkinson's disease (PD). Although it is hypothesized its progress is tightly linked with changes in other motor/non-motor features of PD, it has not been proved yet. The aim of this work is to employ acoustic analysis of sustained phonation in order to identify significant correlates between phonatory measures and motor/non-motor deficits in a two-year follow-up study. For this purpose, we repeatedly quantified a sustained vowel/a/in 51 PD patients who were also assessed by 5 common clinical scales. In addition, a multivariate regression model was trained to predict the motor/non-motor deficits in the horizon of two years. Results suggest that mainly instability in vocal folds oscillation increases with the progress of PD and with overall cognitive decline. Based on the acoustic analysis, the change in clinical scores could be predicted with the error in the range of 11.83-19.60 %.
URI: http://hdl.handle.net/10553/69768
ISBN: 9781538646953
DOI: 10.1109/TSP.2018.8441307
Fuente: 2018 41st International Conference on Telecommunications and Signal Processing, TSP 2018
Colección:Actas de congresos
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