Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/59997
DC FieldValueLanguage
dc.contributor.authorTurkmen, Serhaten_US
dc.contributor.authorPerera, Ericken_US
dc.contributor.authorZamorano, Maria J.en_US
dc.contributor.authorSimó-Mirabet, Paulaen_US
dc.contributor.authorXu, Hanlinen_US
dc.contributor.authorPérez-Sánchez, Jaumeen_US
dc.contributor.authorIzquierdo, Marisolen_US
dc.date.accessioned2019-12-29T18:31:08Z-
dc.date.available2019-12-29T18:31:08Z-
dc.date.issued2019en_US
dc.identifier.issn1422-0067en_US
dc.identifier.otherScopus-
dc.identifier.urihttp://hdl.handle.net/10553/59997-
dc.description.abstractPolyunsaturated fatty acids (PUFA) in parental diets play a key role in regulating n-3 LC-PUFA metabolism of the offspring. However, it is not clear whether this metabolic regulation is driven by the precursors presented in the diet or by the parental ability to synthesize them. To elucidate this, broodstocks of gilthead sea bream with different blood expression levels of fads2, which encodes for the rate-limiting enzyme in the n-3 LC-PUFA synthesis pathway, were fed either a diet supplemented with alpha-linolenic acid (ALA, 18:3n-3) or a control diet. The progenies obtained from these four experimental groups were then challenged with a low LC-PUFA diet at the juvenile stage. Results showed that the offspring from parents with high fads2 expression presented higher growth and improved utilization of low n-3 LC-PUFA diets compared to the offspring from parents with low fads2 expression. Besides, an ALA-rich diet during the gametogenesis caused negative effects on the growth of the offspring. The epigenetic analysis demonstrated that methylation in the promoter of fads2 of the offspring was correlated with the parental fads2 expression levels and type of the broodstock diet.en_US
dc.languageengen_US
dc.relationConsumer driven Production: Integrating Innovative Approaches for Competitive and Sustainable Performance across the Mediterranean Aquaculture Value Chainen_US
dc.relation.ispartofInternational Journal of Molecular Sciencesen_US
dc.sourceInternational journal of molecular sciences [ISSN 1422-0067], v. 20 (24), 6250en_US
dc.subject310502 Pisciculturaen_US
dc.subject.otherDNA methylationen_US
dc.subject.otherDigital droplet PCRen_US
dc.subject.otherModulation of lipid metabolismen_US
dc.subject.otherNutritional programmingen_US
dc.subject.otherParental nutritionen_US
dc.titleEffects of Dietary Lipid Composition and Fatty Acid Desaturase 2 Expression in Broodstock Gilthead Sea Bream on Lipid Metabolism-Related Genes and Methylation of the fads2 Gene Promoter in Their Offspringen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/ijms20246250en_US
dc.identifier.scopus85076488369-
dc.identifier.isi000506840100144-
dc.contributor.authorscopusid36150331400-
dc.contributor.authorscopusid23478009900-
dc.contributor.authorscopusid6701451831-
dc.contributor.authorscopusid57003155700-
dc.contributor.authorscopusid57211362658-
dc.contributor.authorscopusid7003402196-
dc.contributor.authorscopusid7103111891-
dc.identifier.eissn1422-0067-
dc.identifier.issue24-
dc.relation.volume20en_US
dc.investigacionCienciasen_US
dc.type2Artículoen_US
dc.contributor.daisngid31655267-
dc.contributor.daisngid30906193-
dc.contributor.daisngid21764463-
dc.contributor.daisngid34750125-
dc.contributor.daisngid5053388-
dc.contributor.daisngid31500909-
dc.contributor.daisngid34295646-
dc.description.numberofpages20en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Turkmen, S-
dc.contributor.wosstandardWOS:Perera, E-
dc.contributor.wosstandardWOS:Zamorano, MJ-
dc.contributor.wosstandardWOS:Simo-Mirabet, P-
dc.contributor.wosstandardWOS:Xu, HL-
dc.contributor.wosstandardWOS:Perez-Sanchez, J-
dc.contributor.wosstandardWOS:Izquierdo, M-
dc.date.coverdateDiciembre 2019en_US
dc.identifier.ulpgces
dc.description.sjr1,317
dc.description.jcr4,556
dc.description.sjrqQ1
dc.description.jcrqQ1
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptGrupo de Investigación en Acuicultura-
crisitem.author.deptIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGrupo de Investigación en Acuicultura-
crisitem.author.deptIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.deptDepartamento de Biología-
crisitem.author.orcid0000-0003-1569-9152-
crisitem.author.orcid0000-0003-3583-6660-
crisitem.author.parentorgIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.parentorgIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.fullNameZamorano Serrano, María Jesús-
crisitem.author.fullNameIzquierdo López, María Soledad-
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