Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/54929
Título: Radioterapia intraoperatoria con Intrabeam® para el tratamiento del adenocarcinoma de páncreas resecable
Otros títulos: Intraoperative radiotherapy with the Intrabeam® device for the treatment of resectable pancreatic adenocarcinoma
Autores/as: Rahy Martín, Aída Cristina 
Cruz-Benavides, Francisco
Sánchez - Lauro Martínez, María Del Mar 
Rodríguez-Méndez, Álvaro
San Miguel, Íñigo
Lara Jiménez, Pedro Carlos 
Marchena-Gómez, Joaquín 
Clasificación UNESCO: 32 Ciencias médicas
3213 Cirugía
320713 Oncología
320112 Radioterapia
Palabras clave: Intrabeam (R)
Intraoperative radiotherapy
Pancreatic adenocarcinoma
Morbidity
Surgery
Fecha de publicación: 2018
Editor/a: 0009-739X
Publicación seriada: Cirugia Española (Ed. impresa) 
Resumen: Introduction: The application of intraoperative radiation therapy to the tumor bed after resection of pancreatic cancer has been shown to be beneficial in the local control of the disease. The objective of this study was to evaluate the preliminary outcomes after the application of a single intraoperative dose to the tumor bed with a new intraoperative radiotherapy device (Intrabeam (R)) in terms of viability, safety and short-term results.Methods: We studied 5 patients who underwent pancreaticoduodenectomy for resectable pancreatic cancer in which a radiotherapy boost (5 Gy) was intraoperatively applied to the tumoral bed using the portable Intrabeam (R) device, a low-energy point-source X-ray. Postoperative complications, hospital stay and mortality, recurrences and short-term survival were analyzed.Results: Mean patient age was 68 years. All patients had a T3-stage tumor and one of them N1. In 3 patients, R0 resection was performed, while R1 resection was conducted in 2. Perioperative mortality was 0%. The only complications included delayed gastric emptying and postoperative hemorrhage. There were no pancreatic fistulas. During follow-up (mean: 11.2 months), there was a relapse in the patient who had undergone R1 resection.Conclusions: The application of radiotherapy with the Intrabeam (R) device in selected patients has not resulted in increased perioperative morbidity or mortality; therefore, this is a safe procedure for the treatment of resectable cancer.
URI: http://hdl.handle.net/10553/54929
ISSN: 0009-739X
DOI: 10.1016/j.ciresp.2018.04.014
Fuente: Cirugia Espanola[ISSN 0009-739X],v. 96(8), p. 482-487 (Octubre 2018)
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