Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50924
DC FieldValueLanguage
dc.contributor.authorGnaiger, E.en_US
dc.contributor.authorBoushel, R.en_US
dc.contributor.authorSøndergaard, H.en_US
dc.contributor.authorMunch-Andersen, T.en_US
dc.contributor.authorDamsgaard, R.en_US
dc.contributor.authorHagen, C.en_US
dc.contributor.authorDíez-Sánchez, C.en_US
dc.contributor.authorAra, I.en_US
dc.contributor.authorWright-Paradis, C.en_US
dc.contributor.authorSchrauwen, P.en_US
dc.contributor.authorHesselink, M.en_US
dc.contributor.authorCalbet, J. A. L.en_US
dc.contributor.authorChristiansen, M.en_US
dc.contributor.authorHelge, J. W.en_US
dc.contributor.authorSaltin, B.en_US
dc.contributor.otherCalbet, Jose A-
dc.contributor.otherHelge, Jorn-
dc.contributor.otherAra Royo, Ignacio-
dc.contributor.otherschrauwen, patrick-
dc.contributor.otherGnaiger, Erich-
dc.date.accessioned2018-11-24T19:57:33Z-
dc.date.available2018-11-24T19:57:33Z-
dc.date.issued2015en_US
dc.identifier.issn0905-7188en_US
dc.identifier.urihttp://hdl.handle.net/10553/50924-
dc.description.abstractDuring evolution, mitochondrial DNA haplogroups of arctic populations may have been selected for lower coupling of mitochondrial respiration to ATP production in favor of higher heat production. We show that mitochondrial coupling in skeletal muscle of traditional and westernized Inuit habituating northern Greenland is identical to Danes of western Europe haplogroups. Biochemical coupling efficiency was preserved across variations in diet, muscle fiber type, and uncoupling protein‐3 content. Mitochondrial phenotype displayed plasticity in relation to lifestyle and environment. Untrained Inuit and Danes had identical capacities to oxidize fat substrate in arm muscle, which increased in Danes during the 42 days of acclimation to exercise, approaching the higher level of the Inuit hunters. A common pattern emerges of mitochondrial acclimatization and evolutionary adaptation in humans at high latitude and high altitude where economy of locomotion may be optimized by preservation of biochemical coupling efficiency at modest mitochondrial density, when submaximum performance is uncoupled from VO2max and maximum capacities of oxidative phosphorylation.en_US
dc.languageengen_US
dc.publisher0905-7188-
dc.relation.ispartofScandinavian Journal of Medicine and Science in Sportsen_US
dc.sourceScandinavian Journal Of Medicine & Science In Sports[ISSN 0905-7188],v. 25, p. 126-134en_US
dc.subject241106 Fisiología del ejercicioen_US
dc.subject.otherBrown Adipose-Tissue
dc.subject.otherHuman Mtdna
dc.subject.otherSelection
dc.subject.otherHumans
dc.subject.otherHaplogroups
dc.subject.otherEvolution
dc.subject.otherDna
dc.subject.otherCells
dc.subject.otherBioenergetics
dc.subject.otherRespiration
dc.titleMitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and Caucasians in the arctic winteren_US
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.1111/sms.12612
dc.identifier.scopus84948402625-
dc.identifier.isi000365322300023-
dcterms.isPartOfScandinavian Journal Of Medicine & Science In Sports-
dcterms.sourceScandinavian Journal Of Medicine & Science In Sports[ISSN 0905-7188],v. 25, p. 126-134-
dc.contributor.authorscopusid55365839300-
dc.contributor.authorscopusid7003471688-
dc.contributor.authorscopusid36958968500-
dc.contributor.authorscopusid20735070800-
dc.contributor.authorscopusid6506963877-
dc.contributor.authorscopusid55645082100-
dc.contributor.authorscopusid6506330419-
dc.contributor.authorscopusid57201415994-
dc.contributor.authorscopusid6603689982
dc.contributor.authorscopusid36740604300-
dc.contributor.authorscopusid7003942896-
dc.contributor.authorscopusid7004164830-
dc.contributor.authorscopusid7004323423-
dc.contributor.authorscopusid7102525297-
dc.contributor.authorscopusid20334409300-
dc.contributor.authorscopusid7103099936-
dc.description.lastpage134-
dc.description.firstpage126-
dc.relation.volume25-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000365322300023-
dc.contributor.daisngid156181-
dc.contributor.daisngid220476-
dc.contributor.daisngid1592176-
dc.contributor.daisngid3384687-
dc.contributor.daisngid1055810-
dc.contributor.daisngid29246417
dc.contributor.daisngid234106-
dc.contributor.daisngid1978686-
dc.contributor.daisngid238859-
dc.contributor.daisngid7863187-
dc.contributor.daisngid66440-
dc.contributor.daisngid102527-
dc.contributor.daisngid90295-
dc.contributor.daisngid29735273
dc.contributor.daisngid16539595-
dc.contributor.daisngid147585-
dc.contributor.daisngid13919-
dc.identifier.investigatorRIDH-6693-2015-
dc.identifier.investigatorRIDI-7096-2012-
dc.identifier.investigatorRIDNo ID-
dc.identifier.investigatorRIDNo ID-
dc.identifier.investigatorRIDNo ID-
dc.contributor.wosstandardWOS:Gnaiger, E
dc.contributor.wosstandardWOS:Boushel, R
dc.contributor.wosstandardWOS:Sondergaard, H
dc.contributor.wosstandardWOS:Munch-Andersen, T
dc.contributor.wosstandardWOS:Damsgaard, R
dc.contributor.wosstandardWOS:Hagen, C
dc.contributor.wosstandardWOS:Diez-Sanchez, C
dc.contributor.wosstandardWOS:Ara, I
dc.contributor.wosstandardWOS:Wright-Paradis, C
dc.contributor.wosstandardWOS:Schrauwen, P
dc.contributor.wosstandardWOS:Hesselink, M
dc.contributor.wosstandardWOS:Calbet, JAL
dc.contributor.wosstandardWOS:Christiansen, M
dc.contributor.wosstandardWOS:Helge, JW
dc.contributor.wosstandardWOS:Saltin, B
dc.date.coverdateEnero 2015
dc.identifier.ulpgces
dc.description.sjr1,283
dc.description.jcr3,025
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Rendimiento humano, ejercicio físico y salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Educación Física-
crisitem.author.orcid0000-0002-9215-6234-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameLópez Calbet, José Antonio-
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