Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47391
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dc.contributor.authorQuintana Hernández, Domingo Jesúsen_US
dc.contributor.authorMiró Barrachina, María Teresaen_US
dc.contributor.authorIbáñez Fernández, Ignacioen_US
dc.contributor.authorSantana del Pino, Angeloen_US
dc.contributor.authorRojas Hernández, Jaimeen_US
dc.contributor.authorRodríguez García, Javieren_US
dc.contributor.authorQuintana Montesdeoca, María del Pinoen_US
dc.date.accessioned2018-11-23T13:11:47Z-
dc.date.available2018-11-23T13:11:47Z-
dc.date.issued2015en_US
dc.identifier.issn0211-139Xen_US
dc.identifier.urihttp://hdl.handle.net/10553/47391-
dc.description.abstractIntroduction: A longitudinal study was conducted in order to analyze the feasibility, safety, and effects of the practice of mindfulness, relaxation and cognitive stimulation on the evolution of Alzheimer's disease, with the aim of testing the equivalence of these interventions. Material and methods: There were a total of 168 participants with probable Alzheimer's disease (AD) treated with donepezil. In the present article, the 21 participants with advanced AD who completed a follow-up period of 24 months are presented. The participants were grouped into three experimental groups (mindfulness, relaxation, and cognitive stimulation) and one control group. Each group carried out three weekly sessions with bi-annual follow-up measurements (cognition: CAMCOG and MMSE; functionality: RDRS; psychopathology: NPI). Non-parametric analyses were performed. Results: The cognitive function and functionality scores showed no significant differences between the groups. However, the scores in cognitive function of the mindfulness group and the cognitive stimulation group did not decrease in an intra-group analysis. In NPI, there were significant differences between the mindfulness group and the control group by the end of the study (P<.017). Conclusion: The data showed that the treatment with donepezil in combination with mindfulness or cognitive stimulation presented a better clinical evolution than the pharmacological treatment alone or combined with relaxation. These data suggest that these therapeutic alternatives should be investigated further, and that the non-pharmacological treatments should be recommended in clinical practice in order to control the evolution of AD in the long term. In order to confirm these findings, a larger study is necessary.en_US
dc.languageengen_US
dc.relation.ispartofRevista Española de Geriatría y Gerontologíaen_US
dc.sourceRevista Espanola de Geriatria y Gerontologia [ISSN 0211-139X], v. 50(4), p. 168-173en_US
dc.subject32 Ciencias médicasen_US
dc.subject240401 Bioestadísticaen_US
dc.subject120903 Análisis de datosen_US
dc.subject.otherAlzheimer's diseaseen_US
dc.subject.otherClinical pilot studyen_US
dc.titleMindfulness-based stimulation in advanced Alzheimer's disease: a comparative, non-inferiority, clinical pilot studyen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.regg.2014.11.010en_US
dc.identifier.scopus84931571261-
dc.contributor.authorscopusid56173672400-
dc.contributor.authorscopusid56174248500-
dc.contributor.authorscopusid55240227500-
dc.contributor.authorscopusid56554207500-
dc.contributor.authorscopusid35365174300-
dc.contributor.authorscopusid56553861000-
dc.contributor.authorscopusid57053477400-
dc.contributor.authorscopusid56554226900-
dc.description.lastpage173en_US
dc.description.firstpage168en_US
dc.relation.volume50en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.numberofpages6en_US
dc.utils.revisionen_US
dc.date.coverdateJulio 2015en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr0,234
dc.description.sjrqQ4
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR Estadística-
crisitem.author.deptDepartamento de Matemáticas-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Matemáticas-
crisitem.author.orcid0000-0002-6513-4814-
crisitem.author.orcid0000-0003-1276-7594-
crisitem.author.parentorgDepartamento de Matemáticas-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameSantana Del Pino, Ángelo-
crisitem.author.fullNameQuintana Montesdeoca, María Del Pino-
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