Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47238
Title: Effect of lipopolysaccharides from Vibrio alginolyticus on the Mx gene expression and virus recovery from gilthead sea bream (Sparus aurata L.) experimentally infected with Nodavirus
Authors: Bravo, Jimena 
Real Valcárcel, Fernando 
Padilla, D. 
Olveira, J. G.
Grasso, V.
Román, L.
Acosta, F. 
Keywords: Sole Solea-Senegalensis
Viral Nervous Necrosis
Epinephelus-Septemfasciatus
Sevenband Grouper
Antiviral State, et al
Issue Date: 2013
Publisher: 1050-4648
Journal: Fish and Shellfish Immunology 
Abstract: Infections with nodavirus affect a wild and farmed fish species throughout the world, mostly from the marine environment. The aim of this work was to determine the immune status of gilthead sea bream that comes as a result of a Nodavirus infection, induced by activation of the interferon response pathway by lipopolysaccharides from Vibrio alginolyticus and the expression of interferoninduced Mx protein in liver samples. The enhancement of Mx protein gene expression was detected in liver samples of experimentally nodavirus infected fish and, furthermore, the immunostimulant LPS of V. alginolyticus decreased almost three times the virus titration with respect to no-immunized or infected with nodavirus group of fish. (c) 2012 Elsevier Ltd. All rights reserved.
URI: http://hdl.handle.net/10553/47238
ISSN: 1050-4648
DOI: 10.1016/j.fsi.2012.10.012
Source: Fish and Shellfish Immunology[ISSN 1050-4648],v. 34, p. 383-386
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