Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47235
DC FieldValueLanguage
dc.contributor.authorValdivia, J.en_US
dc.contributor.authorReal Valcárcel, Fernandoen_US
dc.contributor.authorAcosta, F.en_US
dc.contributor.authorAcosta, B.en_US
dc.contributor.authorDéniz, S.en_US
dc.contributor.authorRamos-vivas, J.en_US
dc.contributor.authorElaamri, F.en_US
dc.contributor.authorPadilla, D.en_US
dc.contributor.otherAcosta-Hernandez, Begona-
dc.contributor.otherEL AAMRI, FATIMA-
dc.date.accessioned2018-11-23T11:55:04Z-
dc.date.available2018-11-23T11:55:04Z-
dc.date.issued2013en_US
dc.identifier.issn0300-9858en_US
dc.identifier.urihttp://hdl.handle.net/10553/47235-
dc.description.abstractCaseous lymphadenitis is an infectious and contagious disease caused by Corynebacterium pseudotuberculosis, with a worldwide distribution and high prevalence in small ruminant populations. This disease causes significant economic loss in small ruminants through reduced meat, wool, and milk production. C. pseudotuberculosis can also affect horses, domestic and wild large ruminants, swine, and man. It is considered an occupational zoonosis for humans. As part of in vitro investigations of the pathogenesis of C. pseudotuberculosis, this study analyzed its capacity to adhere to and invade the FLK-BLV-044 cell line, derived from ovine embryonic kidney cells. C. pseudotuberculosis showed a measurable capacity to adhere to and invade this cell line with no significant differences between the four strains assessed. The incubation of the cell line at 4 degrees C, pre-incubation with sugars, complete and heat inactivated antiserum, and heat-killed and ultraviolet-killed bacteria produced a significant (P < 0.05) decrease in the invasion efficiency or inability to invade the cell line. Plate counting and fluorescence studies showed intracellular bacteria for up to 6 days. Non-phagocytic cells may therefore act as a suitable environment for C. pseudotuberculosis survival and play a role in the spread of infection and/or maintenance of a carrier state.en_US
dc.languagespaen_US
dc.publisher0300-9858
dc.relation.ispartofVeterinary Pathologyen_US
dc.sourceVeterinary Pathology[ISSN 0300-9858],v. 50, p. 318-323en_US
dc.subject.otherHuman Epithelial-Cellsen_US
dc.subject.otherIntracellular Survivalen_US
dc.subject.otherSalmonella-Typhimuriumen_US
dc.subject.otherInvasionen_US
dc.subject.otherIdentificationen_US
dc.subject.otherPathogensen_US
dc.subject.otherVirulenceen_US
dc.subject.otherProteinen_US
dc.subject.otherPcren_US
dc.titleInteraction of Corynebacterium Pseudotuberculosis With Ovine Cells in Vitroen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1177/0300985812452579en_US
dc.identifier.scopus84874765056-
dc.identifier.isi000330296500016-
dcterms.isPartOfVeterinary Pathology
dcterms.sourceVeterinary Pathology[ISSN 0300-9858],v. 50 (2), p. 318-323
dc.contributor.authorscopusid55352499500-
dc.contributor.authorscopusid7005397318-
dc.contributor.authorscopusid56269311600-
dc.contributor.authorscopusid7003318391-
dc.contributor.authorscopusid7003859353-
dc.contributor.authorscopusid23493408700-
dc.contributor.authorscopusid55618224900-
dc.contributor.authorscopusid7005088705-
dc.description.lastpage323en_US
dc.description.firstpage318en_US
dc.relation.volume50en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000330296500016-
dc.contributor.daisngid1146245-
dc.contributor.daisngid10185393-
dc.contributor.daisngid32158446-
dc.contributor.daisngid935046-
dc.contributor.daisngid878226-
dc.contributor.daisngid1422265-
dc.contributor.daisngid28148410-
dc.contributor.daisngid1854108-
dc.contributor.daisngid1867567-
dc.contributor.daisngid3017971-
dc.contributor.daisngid1039753-
dc.identifier.investigatorRIDK-3822-2017-
dc.identifier.investigatorRIDNo ID-
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Valdivia, J-
dc.contributor.wosstandardWOS:Real, F-
dc.contributor.wosstandardWOS:Acosta, F-
dc.contributor.wosstandardWOS:Acosta, B-
dc.contributor.wosstandardWOS:Deniz, S-
dc.contributor.wosstandardWOS:Ramos-vivas, J-
dc.contributor.wosstandardWOS:Elaamri, F-
dc.contributor.wosstandardWOS:Padilla, D-
dc.date.coverdateMarzo 2013en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-VETen_US
dc.description.sjr1,101
dc.description.jcr2,038
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR Sanidad de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR Grupo de Investigación en Acuicultura-
crisitem.author.deptIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR Sanidad de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR Sanidad de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR Sanidad de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.orcid0000-0001-6526-0354-
crisitem.author.orcid0000-0002-1098-7529-
crisitem.author.orcid0000-0002-0397-4244-
crisitem.author.orcid0000-0003-0201-8338-
crisitem.author.orcid0000-0002-6678-5029-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Investigación en Acuicultura Sostenible y Ec-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.fullNameReal Valcárcel, Fernando-
crisitem.author.fullNameAcosta Arbelo, Félix Antonio-
crisitem.author.fullNameAcosta Hernández, Begoña María-
crisitem.author.fullNameDéniz Suárez, María Soraya-
crisitem.author.fullNamePadilla Castillo, Daniel Fermín-
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