Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47059
Title: Secondary metabolites from two species of tolpis and their biological activities
Authors: Triana Mendez,Jorge 
Marrero, María Teresa
Brouard, Ignacio
León, Francisco 
Lopez Sanchez,Mariana 
Perez Galvan,Francisco Javier 
Rico Santos, Milagros 
López-Monzón, Aroa
Estévez Rosas, Francisco 
UNESCO Clasification: 230690 Química de productos naturales orgánicos
Keywords: Asteraceae
Tolpis proustii
Tolpis lagopoda
Ursane-triterpenes
Taraxastane-triterpenes
Issue Date: 2012
Project: Aislamiento y Sistesis de Productos Naturales Con Actividad Citostitica de Plantas de la Familia Asteraceae Endemicas de Canarias. 
Journal: Molecules 
Abstract: Phytochemical research of two Tolpis species, T. proustii and T. lagopoda, led to the isolation of three new compounds: 30-chloro-3beta-acetoxy-22alfa-hydroxyl-20(21)- taraxastene (1), 3beta,22alfa-diacetoxy-30-ethoxy-20(21)-taraxastene (2) and 3beta,28-dihydroxy- 11alfa-hydroperoxy-12-ursene (3). The structures of the new compounds were elucidated by means of extensive IR, NMR, and MS data and by comparison of data reported in the literature. The in vitro antioxidant activities of the extracts were assessed by the DPPH and ABTS scavenging methods. The cytotoxicity of several known compounds and its derivatives was also assessed against human myeloid leukemia K-562 and K-562/ADR cell lines.
URI: http://hdl.handle.net/10553/47059
ISSN: 1420-3049
DOI: 10.3390/molecules171112895
Source: Molecules [ISSN 1420-3049], v. 17 (11), p. 12895-12909
Rights: by-nc-nd
Appears in Collections:Artículos
Thumbnail
Adobe PDF (246,61 kB)
Show full item record

SCOPUSTM   
Citations

4
checked on Jul 3, 2022

WEB OF SCIENCETM
Citations

4
checked on Jul 3, 2022

Page view(s)

28
checked on May 21, 2022

Download(s)

5
checked on May 21, 2022

Google ScholarTM

Check

Altmetric


Share



Export metadata



Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.