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Title: Eosinophilic leukemia in three African pygmy hedgehogs (Atelerix albiventris) and validation of Luna stain
Authors: Martínez-Jiménez, David
Garner, Bridget
Coutermarsh-Ott, Sheryl
Burrell, Caitlin
Clark, Sabrina
Nabity, Mary
Diaz Delgado, Josue
Rodrigues-Hoffmann, Aline
Zaks, Karen
Proença, Laila
Divers, Stephen
Saba, Corey
Cazzini, Paola
UNESCO Clasification: 310907 Patología
Keywords: African pygmy hedgehog
Atelerix albiventris
Eosinophilic leukemia
Luna stain
Myeloproliferative disease, et al
Issue Date: 2017
Publisher: 1040-6387
Journal: Journal of Veterinary Diagnostic Investigation 
Abstract: Neoplasia is usually encountered in the African pygmy hedgehog at a mean age of 3.5 y, and malignancy is common. Myelogenous leukemias are rarely reported in hedgehogs. We describe 3 cases of eosinophilic leukemia in adult, middle-aged (mean age: 2.3 y) hedgehogs, for which prognosis appears grave. In 1 case, attempted treatment was unsuccessful, and in all 3 cases, the disease course was rapid and all died soon after diagnosis. Blood smear evaluation, along with complete blood count, was critical in making the diagnosis in all cases. Luna stain was validated and used to better visualize eosinophils in cytologic and histologic sections. Electron microscopy confirmed the presence of specific granules in hedgehog eosinophils.
ISSN: 1040-6387
DOI: 10.1177/1040638716687603
Source: Journal of Veterinary Diagnostic Investigation [ISSN 1040-6387], v. 29, p. 217-223
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