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http://hdl.handle.net/10553/44424
Título: | Functional distribution of Ca2+-coupled P2 purinergic receptors among adrenergic and noradrenergic bovine adrenal chromaffin cells | Autores/as: | Tomé, Ângelo R. Castro, Enrique Santos, Rosa M. Rosário, Luís M. |
Clasificación UNESCO: | 2403 Bioquímica | Palabras clave: | Tyrosine Hydroxylase Chromaffin Cell Bovine chromaffin cell Frequency Distribution Histogram Virtual Absence |
Fecha de publicación: | 2007 | Publicación seriada: | BMC Neuroscience | Resumen: | Adrenal chromaffin cells mediate acute responses to stress through the release of epinephrine. Chromaffin cell function is regulated by several receptors, present both in adrenergic (AD) and noradrenergic (NA) cells. Extracellular ATP exerts excitatory and inhibitory actions on chromaffin cells via ionotropic (P2X) and metabotropic (P2Y) receptors. We have taken advantage of the actions of the purinergic agonists ATP and UTP on cytosolic free Ca2+ concentration ([Ca2+]i) to determine whether P2X and P2Y receptors might be asymmetrically distributed among AD and NA chromaffin cells. | URI: | http://hdl.handle.net/10553/44424 | ISSN: | 1471-2202 | DOI: | 10.1186/1471-2202-8-39 | Fuente: | BMC Neuroscience [ISSN 1471-2202], v. 8, Article number 39, (Junio 2007) |
Colección: | Artículos |
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