Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/43429
Título: Efficacy of metformin therapy in patients with type 2 diabetes mellitus poorly controlled with insulin therapy
Autores/as: Boronat Cortés, Mauro 
Marrero Arencibia, D.
La Roche Brier, F.
Ojeda Pino, A.
Carrillo Domínguez, A.
Novoa Mogollón, F. J.
Clasificación UNESCO: 32 Ciencias médicas
Fecha de publicación: 2000
Editor/a: 0014-2565
Publicación seriada: Revista clínica española (Ed. impresa) 
Resumen: Combined treatment with insulin plus metformin could be a good alternative to improve the glycemic control in patients with type 2 diabetes mellitus poorly controlled with insulin therapy. We retrospectively studied 21 obese insulin-treated type 2 diabetic patients with deficient metabolic control (HbAlc 9.2+/-1.2%) who were treated with metformin for a minimum of 8 months. After 4 months of treatment, a significant decrease in the percentage of HbAlc was observed (Delta HbAlc-1.07+/-.12%; p<0.01), with maintained values since then. Non changes in body weight or insulin requirement were noted. Our results suggest that the addition of metformin to insulin treatment is a safe and effective strategy for the improvement of glycemic control among obese type 2 diabetic patients.
URI: http://hdl.handle.net/10553/43429
ISSN: 0014-2565
Fuente: Revista Clinica Española [ISSN 0014-2565], v. 200, p. 74-76
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