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http://hdl.handle.net/10553/43429
Título: | Efficacy of metformin therapy in patients with type 2 diabetes mellitus poorly controlled with insulin therapy | Autores/as: | Boronat Cortés, Mauro Marrero Arencibia, D. La Roche Brier, F. Ojeda Pino, A. Carrillo Domínguez, A. Novoa Mogollón, F. J. |
Clasificación UNESCO: | 32 Ciencias médicas | Fecha de publicación: | 2000 | Editor/a: | 0014-2565 | Publicación seriada: | Revista clínica española (Ed. impresa) | Resumen: | Combined treatment with insulin plus metformin could be a good alternative to improve the glycemic control in patients with type 2 diabetes mellitus poorly controlled with insulin therapy. We retrospectively studied 21 obese insulin-treated type 2 diabetic patients with deficient metabolic control (HbAlc 9.2+/-1.2%) who were treated with metformin for a minimum of 8 months. After 4 months of treatment, a significant decrease in the percentage of HbAlc was observed (Delta HbAlc-1.07+/-.12%; p<0.01), with maintained values since then. Non changes in body weight or insulin requirement were noted. Our results suggest that the addition of metformin to insulin treatment is a safe and effective strategy for the improvement of glycemic control among obese type 2 diabetic patients. | URI: | http://hdl.handle.net/10553/43429 | ISSN: | 0014-2565 | Fuente: | Revista Clinica Española [ISSN 0014-2565], v. 200, p. 74-76 |
Colección: | Artículos |
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