Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/43385
Title: Immunohistopathologic characterization of a dermal melanocytoma-acanthoma in a German shepherd dog
Authors: Espinosa de los Monteros y Zayas, Antonio 
Martín de Las Mulas, J.
Fernández Rodríguez, Antonio Jesús 
Orós Montón, Jorge Ignacio 
Rodríguez Guisado, Francisco 
UNESCO Clasification: 310907 Patología
310903 Inmunología
Keywords: Dogs
Immunohistochemistry
Melanocytoma-acanthoma
Skin
Issue Date: 2000
Publisher: 0300-9858
Journal: Veterinary Pathology 
Abstract: A cutaneous melanocytoma-acanthoma in a 2-year-old female German Shepherd Dog was characterized by the presence of two populations of neoplastic cells: epithelial and melanocytic. The epithelial component consisted of nests of well-differentiated stratified squamous epithelium closely associated with neoplastic melanocytes. The epithelial cells immunoreacted with both monoclonal and polyclonal anti-cytokeratin antibodies, and immunoreaction to S-100 protein and vimentin was observed in the melanocytic cells. This rare pigmented skin neoplasm of the dog apparently has a benign behavior.
URI: http://hdl.handle.net/10553/43385
ISSN: 0300-9858
Source: Veterinary Pathology [ISSN 0300-9858], v. 37, p. 268-271
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