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Title: CALR mutation characterization in myeloproliferative neoplasms
Authors: Bilbao-Sieyro, Cristina 
Florido, Yanira
Gómez Casares, María Teresa 
UNESCO Clasification: 32 Ciencias médicas
320504 Hematología
Keywords: CALR
myeloproliferative neoplasms
type-1/2-like mutations
Issue Date: 2016
Journal: Oncotarget 
Abstract: Identification of somatic frameshift mutations in exon 9 of the calreticulin gene (CALR) in myeloproliferative neoplasms (MPNs) in December of 2013 has been a remarkable finding. It has provided a new molecular diagnostic marker, particularly in essential thrombocythemia (ET) and primary myelofibrosis (PMF), where is the second most common altered gene after JAK2V617F.
ISSN: 1949-2553
DOI: 10.18632/oncotarget.10376
Source: Oncotarget [ISSN 1949-2553], v. 7 (33), p. 52614-52617
Rights: by-nc-nd
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