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Title: Late bone metastasis from an apparently benign oncocytic follicular thyroid tumor
Authors: Boronat Cortés, Mauro 
Cabrera Galván, Juan José 
Perera, Carmen
Isla, Concepción
Novoa Mogollón, Francisco 
UNESCO Clasification: 32 Ciencias médicas
320502 Endocrinología
Keywords: Bone metastasis
Thyroid tumor
Issue Date: 2013
Journal: Endocrinology, Diabetes and Metabolism Case Reports 
Abstract: A man underwent total thyroidectomy for goiter when he was 62 years old. The pathology report informed on a 5.5 cm oncocytic follicular adenoma and a 3.5 mm papillary microcarcinoma. Due to the papillary tumor, he was treated with ablative radioiodine therapy and suppressive doses of levothyroxine. After uneventful follow-up for 9 years, increased levels of serum thyroglobulin were detected. Further imaging studies including a whole body scan (WBS) after an empirical dose of 200 mCi 131I were negative. Two years later, a 99mTc SestaMIBI WBS and a 2-[18F]-fluoro-2-deoxy-D-glucose positron-emission tomography showed a well-delimited focal uptake in the right femur. A bone biopsy of the lesion demonstrated metastasis of follicular thyroid carcinoma. Retrospective histological reexamination of available material from the primary oncocytic thyroid tumor failed to reveal definitive traits of malignancy.
ISSN: 2052-0573
DOI: 10.1530/EDM-13-0051
Source: Endocrinology, Diabetes and Metabolism Case Reports [ISSN 2052-0573], v. 2013(1)
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