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Issue DateTitleAuthor(s)
12020Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer AgentsOliva, Paola; Onnis, Valentina; Balboni, Elisa; Hamel, Ernest; Estévez-Sarmiento, Francisco; Quintana Aguiar, José Martín ; Estévez Rosas, Francisco Jesús ; Brancale, Andrea; Ferla, Salvatore; Manfredini, Stefano; Romagnoli, RomeoSynthesis and Biological Evaluation.pdf.jpg
22020Melatonin induces melanogenesis in human SK-MEL-1 melanoma cells involving glycogen synthase kinase-3 and reactive oxygen speciesPerdomo Díaz, Juan ; Quintana, Carlos; González Gordillo,Ignacio ; Hernández González, Inmaculada Servanda ; Rubio Sánchez, Sara ; Loro Ferrer, Juan Francisco ; Reiter, Russel J.; Estévez Rosas, Francisco Jesús ; Quintana Aguiar, José Martín Melatonin Induces Melanogenesis in Human SK-MEL-1 Melanoma Cells Involving Glycogen Synthase Kinase-3 and Reactive Oxygen Species.pdf.jpg
32019Signal transduction pathways involved in the stimulation of melanogenesis by melatonin in the human melanoma cell line SK-MEL-1Perdomo, Juan ; Quintana, Carlos; Rubio Sánchez, Sara ; González Robayna, Ignacio Javier ; Hernandez Gonzalez, Inmaculada ; Loro-Ferrer, Juan Francisco ; Estevez, Francisco ; Quintana Aguiar, José Martín 
42019Apoptosis induction and activation of the mitogen-activated protein kinase pathway in human U-937 leukaemia cells by the synthetic flavanone 6-methoxy-2-(naphthalen-1-yl)-chroman-4-oneEstévez Rosas, Francisco Jesús ; Saavedra, Ester; Del Rosario García, Henoc ; Brouard, Ignacio; Hernandez-Garces, Judith; Garcia, Celina; Quintana Aguiar, José Martín 
52019Apoptosis induction by an alpha-bromoacryloylamido indolyl-pyridinyl-propenone derivative on human melanoma cellsRodriguez, Irene; Quintana, Jose ; Prencipe, Filippo; Oliva, Paola; Romagnoli, Romeo; Francisco Loro, Juan ; Estevez, Francisco 
62019New findings in molecular mechanisms responsible of the antitumoral in vitro effect of CM728 in MDA-MB-231 cell lineSpinola, Elena; Jimenez, Roberto; Monteror, Monteror; McNaughton-Smith, Grant; Quintana, Jose ; Estevez, Francisco ; Nicolas Diaz-Chico, Bonifacio ; Pandiella, Atanasio; Carlos Diaz-Chico, Juan 
72019Natural occurring sesquiterpene lactone Spiciformin induces apoptosis and activation of mitogen-activated protein kinase pathway on human tumour cell lines.Rubio Sánchez, Sara ; Estevez, Francisco ; Saavedra Santana, Ester Gloria ; Said, Mercedes; Eiroa Martínez, José Luis ; Quintana, Jose ; Estevez-Sarmiento, Francisco 
82019The synthetic flavanone 6-methoxy-2-(naphthalen-1-yl)chroman-4-one induces apoptosis and activation of the MAPK pathway in human U-937 leukaemia cellsSaavedra Santana, Ester Gloria ; Del Rosario, Henoc ; Brouard, Ignacio; Hernández-Garcés, Judith; García, Celina; Quintana, José ; Estévez, Francisco 
92019A novel naphthoquinone-coumarin hybrid that inhibits BCR-ABL1-STAT5 oncogenic pathway and reduces survival in imatinib-resistant chronic myelogenous leukemia cellsMartín-Rodríguez, Patricia ; Guerra, Borja ; Hueso-Falcón, Idaira; Aranda Tavío, Haidee Magdalena ; Díaz-Chico, Juan ; Quintana, José; Estévez, Francisco ; Díaz-Chico, Bonifacio ; Amesty, Angel; Estévez-Braun, Ana; Fernández-Pérez, Leandro A Novel Naphthoquinone .pdf.jpg
1020196′-Benzyloxy-4-bromo-2′-hydroxychalcone is cytotoxic against human leukaemia cells and induces caspase-8- and reactive oxygen species-dependent apoptosisSaavedra, Ester; Del Rosario, Henoc; Brouard, Ignacio; Quintana, José ; Estévez, Francisco 
112018Secondary metabolites from two Hispaniola Ageratina species and their cytotoxic activityEiroa, José Luis ; Triana, Jorge; Pérez, Francisco J. ; Castillo, Quírico A.; Brouard, Ignacio; Quintana, José ; Estevez, Francisco ; León, Francisco
1220183 '-Hydroxy-3,4 '-dimethoxyflavone-induced cell death in human leukaemia cells is dependent on caspases and reactive oxygen species and attenuated by the inhibition of JNK/SAPKBrouard, Ignacio; Estévez Sarmiento, Francisco; Hernandez Brito, Elisa ; León, Francisco; García, Celina; Quintana Aguiar, José Martín ; Estévez, Francisco 
132018Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3 ',4 ',5 '-trimethoxyphenyl)-3-(2 '-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approachPreti, Delia; Romagnoli, Romeo; Rondanin, Riccardo; Cacciari, Barbara; Hamel, Ernest; Balzarini, Jan; Liekens, Sandra; Schols, Dominique; Estévez Sarmiento, Francisco; Quintana, José ; Estévez, Francisco 
142018Anticancer properties of the abietane diterpene 6,7-dehydroroyleanone obtained by optimized extractionGarcia, Catarina; Oliveira Silva, Catarina; Monteiro, Carlos M.; Nicolai, Marisa; Viana, Ana; Andrade, Joana M.; Barasoain, Isabel; Stankovic, Tijana; Quintana, Jose ; Hernandez Gonzalez, Inmaculada ; González Robaina, Ignacio J. ; Estevez, Francisco ; Díaz-Lanza, Ana María; Reis, Catarina P.; Afonso, Carlos A. M.; Pešić, Milica; Rijo, Patricia
152018Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cellsRomagnoli, Romeo; Prencipe, Filippo; Lopez-Cara, Luisa Carlota; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Estévez-Sarmiento, Francisco ; Quintana, Jose ; Estévez, Francisco 
162018Recent Advances on Cytotoxic Sesquiterpene LactonesQuintana, José ; Estévez, Francisco 
172018Novel naphthoquinone-coumarin hybrids as inhibitors of BCR-ABL-STAT5 signaling pathway in chronic myelogenous leukemiaMartín Rodríguez, Patricia ; Guerra, B. ; Hueso-Falcón, I.; Aranda Tavio, Haidee ; Guerra Rodríguez, Miguel A. ; Díaz Chico, Juan Carlos ; Quintana, José ; Estevez, F. ; Díaz-Chico, J. C. ; Amesty, A.; Estévez-Braun, A.; Fernández Pérez, Leandro Fco 
182018Melatonin stimulates melanogenesis via up-regulation of tyrosinase and tyrosinaserelated protein 1 in the human melanoma cell line sk-mel-1Perdomo Díaz, Juan ; Quintana, C.; Rubio Sánchez, Sara ; Gonzalez, I.; Hernandez, I. ; Loro, J. F. ; Estevez, F. ; Quintana, J. 
192018Ethanol increases sensitivity of human myeloid U937 cells to hyperthermia - induced ApoptosisQuintana, M.; González Robaina, Ignacio J. ; Hernandez, I. ; Rubio Sánchez, Sara ; Perdomo, Juan ; Estevez, F. ; Quintana, J. 
2020173 '-Hydroxy-3,4 '-dimethoxyflavone blocks tubulin polymerization and is a potent apoptotic inducer in human SK-MEL-1 melanoma cellsEstevez-Sarmiento, Francisco; Said, Mercedes ; Brouard, Ignacio; Leon, Francisco; Garcia, Celina; Quintana, Jose ; Estevez, Francisco